iS Clinical Super Serum Advance+

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iS Clinical Super Serum Advance
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Free on Orders $45+

iS Clinical Super Serum Advance+

Get enhanced anti-aging and skin brightening properties! This replaces the original formulation with 15% L-Ascorbic acid and has been combined with bio-identical Copper Tripeptide Growth Factor to help hypertrophic scar tissue, reduces fine stretch marks, safely lightens, corrects hyper-pigmentation and provides UV photo-protection.

Available Sizes:

  • 0.5 oz
  • 1.0 oz


  • Helps reduce the appearance of fine lines and wrinkles
  • Helps improve the look of hypertrophic (raised) scar tissue and fine stretch marks
  • Safely brightens and helps visibly diminish uneven skin tone
  • Provides support against environmental aggressors
  • Provides extremely powerful antioxidant protection
  • Paraben-free
  • Oncology friendly

Key Ingredients:

  • L-Ascorbic Acid (Vitamin C) Advance+ - A potent time-released antioxidant that stimulates collagen synthesis and promotes wound healing
  • Centella Asiatica - An antioxidant that stimulates collagen synthesis, improves microcirculation, and promotes wound healing
  • Calcium Pantothenate (Vitamin B5) - Increases cellular integrity and efficiency
  • Arbutin - This extract helps visibly decrease the signs of hyperpigmentation by inhibiting melanin producing enzymes
  • Polyporus Umbellatus (Mushroom) Extract - Controls hyperpigmentation and has antimicrobial, antibacterial, antibiotic properties
  • Copper Tripeptide Growth Factor - This peptide stimulates collagen synthesis and increases and regulates proteins and DNA in dermal wounds



Water/ Aqua/ Eau, Ascorbic Acid, Hyaluronic Acid, Pentylene Glycol, Urea, Glucose, Guanidine, Tripeptide-1, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Calcium Pentothenate, Asiaticoside, Asiatic Acid, Zinc Sulfate, Glycerin, Phenoxyethanol

FREE iS Clinical Gift with Purchase

FREE Forever Young Swag Bag
Get a FREE iS Clinical Forever Young Swag Bag with $175 iS Clinical Purchase A $45 Value!

Product Reviews (5 Reviews)

  • 5
    IS Clinical Super Serum Advance

    Posted by Cindy on 20th Mar 2022

    My dermatologist first recommended this serum for my aging skin. It seems to diminish age spots and is very healing too. I use it every morning under my foundation.

  • 5
    Great product!

    Posted by Maureen on 25th Aug 2017

    I am 100 percent totally pleased with my purchase and with follow-up customer service! I have signed up for your newsletters and plan on shopping again.

  • 4

    Posted by Kls on 4th May 2015

    Sticky on my hands, but works very well in improving my complexion

  • 5

    Posted by Kristin on 11th Nov 2013

    Love it! Great product!

  • 5
    superior Vitamin C!

    Posted by K. Reece on 11th Nov 2013

    I was using the Skinceuticals C & E + Ferulic but this is by far a better product! I have seen more results and my skin looks ravishing!

Customer Testimonials