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iS Clinical C&E Serum Advance+ is a paraben-free, powerful antioxidant serum that hydrates and treats your skin. This serum combines 15% vitamin C with vitamin E to improve the overall health of the skin. The alpha-Tocopherol (vitamin E) works synergistically with the chirally correct L-ascorbic acid (vitamin C) to provide over four times the benefits of vitamin C alone. The iS Clinical C&E Serum Advance+ reduces the appearance of wrinkles and fine lines while improving tone and texture.