iS Clinical Active Serum

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iS Clinical Active Serum
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Free on Orders $45+

iS Clinical Active Serum 0.5 & 1.0 oz

Get fast acting and long term effects with this best seller! This serum not only reduces the appearance of fine lines and wrinkles, but also addresses concerns such as uneven skin tone and acne. Potent activity will be noted upon application as evidenced by a cool tingling sensation and great for both women and men of all ages.

Available Sizes:

  • 0.5 oz
  • 1.0 oz


  • Reduces the appearance of fine lines and wrinkles
  • Diminishes the appearance of uneven skin tone and blemishes
  • Smooths and softens
  • Gives the appearance of smaller pores
  • Provides both rapid and long-term noticeable results
  • Paraben-free

Key Ingredients:

  • Sugar Cane Extract - This extract is a source of glycolic acid, which aids in exfoliation in order to renew your complexion
  • Bilberry Extract - This extract is a source of lactic acid, which is another natural exfoliant that has moisturizing capabilities
  • White Willow Bark Extract - This extract is a source of salicylic acid, which deep cleans the pores of your skin while also exfoliating
  • Arbutin & Mushroom Extract - This extract helps visibly decrease the signs of hyperpigmentation by inhibiting melanin producing enzymes



Water/Aqua/Eau, Glycerin, Glyceryl Polyacrylate, Butylene Glycol, SD Alcohol 30, Saccharum Officinarum (Sugar Cane) Extract, Vaccinium Myrtillus (Bilberry) Extract, Triethanolamine, Arbutin, Salix Alba (Willow) Bark Extract, Polyporus Umbellatus (Mushroom) Extract, Menthol, Phenoxyethanol

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Product Reviews (12 Reviews)

  • 5
    Is Clinical active serum

    Posted by Jasminka Gille on 13th Dec 2021

    Beste serum was ich bis jetzt ausprobiert habe, seine preis berechtigt, kann nur weiter empfehlen

  • 5
    Awesome Serum

    Posted by Brigitte on 30th Nov 2021

    In my opinion, this is one of the best serums available. It goes on easy with a nice little tingle (I love it the tingle). I have noticed an overall clearer complexion with using this serum. I joke that it is magic in a bottle as I struggle with acne and large pores. I still have a few blemishes pop up mostly around the time of my period. But with this serum, they quickly come and go. Buy this! You will not regret it.

  • 5
    As expected

    Posted by Wendy on 23rd Nov 2016

    Item was as expected and on time. I recommend this seller

  • 5
    I use it as a spot treatment too

    Posted by Jade on 3rd Jun 2016

    Work on my pimples, bug bits, almost anything. I love this stuff!

  • 5
    Works for everything

    Posted by Grace on 6th Feb 2014

    This serum is a true panacea for all of my skin issues. Blemishes and redness, mostly, but I've put it on a budding cold sore and it stopped it in its tracks! Not bad!

  • 4
    My Must - Have

    Posted by Unknown on 11th Nov 2013

    This product was recommended for me because of my hormonal acne. I have to admit, I was disappointed that I didn't see immediate results. However, using Active Serum after cleansing with my Clarisonic has really made a difference! I used to hate my skin and it was so embarrassing. I still get an occasional blemish, but it isn't nearly as bad, big or doesn't last as long. I use this all over my face for a brighter complexion, and I love the clean, tingly feeling. The 1 oz size has also lasted me a lot longer than I thought it would.

  • 5
    See Results FAST

    Posted by Maurin on 11th Nov 2013

    Received this in a sample size and used it for close to 2 weeks and my friend could not stop going on and on about how smooth my skin was. This is a fantastic product.

  • 5

    Posted by Chandra on 11th Nov 2013

    I have to say sorry for the long review, but I felt it best to describe my results and experience. I received a sample of active serum through Beautystoredepot's facebook giveaways. I was looking for anything to combat age spots, premature aging as well as adult acne, all of which this product promises to improve. \n About 8 years ago I had a chemical peel done for my adult acne and silly me forgetting the advice of the asthetician spent the next day in the sun with my girls. If I could go back in time that would be the one day I would change. The result was severe hyper-pigmentation all over my face. Through the years I have tried many expensive treatments and products to decrease the discoloration, including photo facials and more peels. While the treatments worked great, every time I went in the sun (with tons of 80 SPF sunblock) the hyper-pigmentation would return leading to another treatment. I live in Texas and love spending time on the water, so for me this was very difficult. As for premature aging while minimal I have moderately deep creases on my forehead that I have considered using botox to hide. And then there is the lovely adult acne... I tend to be prone to cystic acne. Getting large blemishes that love to stick around for a few weeks. \nOk, now on to Active serum. I have started using this product with the Hydra Cool (Love that one to) which I received as a sample. Almost immediately I noticed a decrease in the size of blemishes and the amount of time they were present. As others have reviewed it is a great spot treatment. Most blemishes were gone within 2-4 days with the stubborn ones taking less than a week. The moderate creases on my forehead are now minimal after 2 months of using every other day. As for the hyper-pigmentation, it is almost completely gone!!!!! I have spent multiple days on the water and camping this summer and have had NO recurrence of the hyper-pigmentation. I cannot express how excited and thankful I am to Beautystoredepot for allowing me to try this amazing product. I know the cost is high, but for me the gain is priceless!!!

  • 5
    5 stars

    Posted by Robin B on 11th Nov 2013

    I love this product. Does everything it promises. Five star rating from me :)

Press Release

iS Clinical Active Serum Featured in Marie Claire Magazine

Customer Testimonials