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iS Clinical Active Serum

Item # ISASERUM-1 Customer Rating:
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iS Clinical Active Serum

Active Serum Clinical Studies Prove:

  • Acne - 94% reduction in acne
  • Aging - 65% reduction in fine lines and wrinkles
  • Hyper pigmentation - 57% reduction in pigment irregularities

iS Clinical Active Serum is an ANTI-AGING, SMOOTHING, LIGHTENING, ANTI-ACNEIC, ACTIVE serum. Our exceptional multipurpose formula, is designed to generate rapid and dramatic improvements in overall skin quality. ACTIVE SERUM diminishes fine lines and wrinkles, evens pigmentation, smoothes, and controls acne. ACTIVE SERUM is widely endorsed by leading physicians and experts, who describe ACTIVE SERUM as remarkable, amazing, miraculous, and one of the most important discoveries in the field of skincare. ACTIVE SERUM begins working immediately upon application, as demonstrated by an active tingling sensation. This phenomenal formula absorbs deep within the dermal layers where maximum benefits will be achieved. Extremely sophisticated formulation technology enables ACTIVE SERUM to precisely affect the skin cells themselves, truly providing results on a cellular level.

Size options:

  • 1 oz
  • .5 oz


Apply either to entire face or as a spot treatment morning and/or night.


Sugar Cane Extract (a source of Glycolic Acid), Bilberry Extract (a source of Lactic Acid), Willow Bark Extract (a source of Salicylic Acid), Arbutin, Mushroom Extract (a source of Kojic Acid), Menthol.

FREE GIFT! Receive a FREE 2 oz Cleansing Complex with purchase of this product - valued at $24 - Limited time only!

FREE GIFT! Receive a FREE iS Forever Young Swag Bag with iS Clinical Purchases of $50 and up - valued at $27 - Limited time only! Click here to see your gift.

Write your own product review

  1. I use it as a spot treatment too 5 Star Review

    Posted by on 3rd Jun 2016

    Work on my pimples, bug bits, almost anything. I love this stuff!

  2. Works for everything 5 Star Review

    Posted by on 6th Feb 2014

    This serum is a true panacea for all of my skin issues. Blemishes and redness, mostly, but I've put it on a budding cold sore and it stopped it in its tracks! Not bad!

  3. My Must - Have 4 Star Review

    Posted by on 11th Nov 2013

    This product was recommended for me because of my hormonal acne. I have to admit, I was disappointed that I didn't see immediate results. However, using Active Serum after cleansing with my Clarisonic has really made a difference! I used to hate my skin and it was so embarrassing. I still get an occasional blemish, but it isn't nearly as bad, big or doesn't last as long. I use this all over my face for a brighter complexion, and I love the clean, tingly feeling. The 1 oz size has also lasted me a lot longer than I thought it would.

  4. See Results FAST 5 Star Review

    Posted by on 11th Nov 2013

    Received this in a sample size and used it for close to 2 weeks and my friend could not stop going on and on about how smooth my skin was. This is a fantastic product.

  5. PRICELESS! 5 Star Review

    Posted by on 11th Nov 2013

    I have to say sorry for the long review, but I felt it best to describe my results and experience. I received a sample of active serum through Beautystoredepot's facebook giveaways. I was looking for anything to combat age spots, premature aging as well as adult acne, all of which this product promises to improve. \n About 8 years ago I had a chemical peel done for my adult acne and silly me forgetting the advice of the asthetician spent the next day in the sun with my girls. If I could go back in time that would be the one day I would change. The result was severe hyper-pigmentation all over my face. Through the years I have tried many expensive treatments and products to decrease the discoloration, including photo facials and more peels. While the treatments worked great, every time I went in the sun (with tons of 80 SPF sunblock) the hyper-pigmentation would return leading to another treatment. I live in Texas and love spending time on the water, so for me this was very difficult. As for premature aging while minimal I have moderately deep creases on my forehead that I have considered using botox to hide. And then there is the lovely adult acne... I tend to be prone to cystic acne. Getting large blemishes that love to stick around for a few weeks. \nOk, now on to Active serum. I have started using this product with the Hydra Cool (Love that one to) which I received as a sample. Almost immediately I noticed a decrease in the size of blemishes and the amount of time they were present. As others have reviewed it is a great spot treatment. Most blemishes were gone within 2-4 days with the stubborn ones taking less than a week. The moderate creases on my forehead are now minimal after 2 months of using every other day. As for the hyper-pigmentation, it is almost completely gone!!!!! I have spent multiple days on the water and camping this summer and have had NO recurrence of the hyper-pigmentation. I cannot express how excited and thankful I am to Beautystoredepot for allowing me to try this amazing product. I know the cost is high, but for me the gain is priceless!!!

  6. 5 stars 5 Star Review

    Posted by on 11th Nov 2013

    I love this product. Does everything it promises. Five star rating from me :)

  7. you can feel it working 5 Star Review

    Posted by on 11th Nov 2013

    It tingles when you put it on.... I like it. Know its working.

  8. I agree 5 Star Review

    Posted by on 11th Nov 2013

    I also use it for spot treating pimples. Works great!

  9. Great for spot treatmet too 5 Star Review

    Posted by on 11th Nov 2013

    Although this works great for acne in general... it also works great as a spot treatment for stubborn pimples.

iS Clinical Active Serum Featured in Marie Claire Magazine