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CosMedix Refine Plus .5 oz

Item # 8555217 Customer Rating:
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Cosmedix Refine Plus .5 oz.

Cosmedix Refine 8% is a trans-retinol serum as potent as Retinoic Acid. It is chirally corrected to reduce irritation and photo sensitivity with increased effectiveness. Improves skin's texture,smoothness, and firmness. Essential for the generation and function of skin cells and collagen/elastin production. Helps dispersion of melanocytes bunching to break up stubborn hyper pigmentation. Comparable to .1 Retinoic Acid. This powerful concentration of chirally corrected Vitamin A serum takes Refine 4% to the next level for enhanced results. Its collagen repair stimulating properties make it a potent anti-aging tool. Benefits: Increases cellular turnover Less irritation/redness than with other retinoids Stimulates collagen/elastin/GAG production Reduces fine lines/signs of aging Improves skin texture and color Anti-acne/anti-bacterial/anti-sebum.


  • For acne Blemished skin
  • Hyperpigmentation
  • Melasma
  • Sun damaged/stressed skin (face and body)
  • Fine lines and wrinkles
  • Enlarged/clogged pores


  • Apply a pea-sized amount to clean skin every other evening until tolerance allows for nightly use.
  • Do NOT apply to eyelids!
  • Discontinue use if redness or irritation occurs; resume at a lower dosage after discomfort has subsided.
  • May experience mild peeling.
  • Use caution when applying to neck and chest area.


Aqua (Water), Hamamelis Virginiana (Witch Hazel) Water, Retinol, Cassia Angustifolia Seed Polysaccharide, Glycerin, Sodium Lactate, Proline (L), Sodium PCA, Sodium Hyaluronate (L), Squalane, Dimethicone Copolyol, Helianthus Annuus (Sunflower) Seed Oil, Galactoarabinan, Xanthan Gum, Benzyl Alcohol, D-glucuronic Acid, Santalum Album (Sandalwood) Oil, Jasminum Officinale (Jasminum) Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oi

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  1. Best thing I've used 5 Star Review

    Posted by on 18th Sep 2015

    This is a fantastic product and my very only complaint is that never, ever has the pump lasted/continued to function more than a couple of times. There's something wrong with ALL of them.

    But for the simple blemish to age spots this stuff works. I went to see a derm recently to get my first fillers and she said: "you clearly started using retinol products the day they went on the market." and ya know, I hadn't.

    Be careful on your neck though!

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