iS Clinical Complex Treatments are extremely target oriented for such concerns as: anti-aging, rosacea, and hyperpigmentation. Best sellers, Youth Complex and Youth Eye Complex are scientifically proven to deliver results in as little as an hour! And you can't forget about White Lightening Complex. A clinical study proved that 84% of participants reported overall skin lightening. It also showed a 37% reduction in the production of melanin over 72 hours. All subjects experienced absolutely no side effects leading 81% to continue use of the product.